AutoGen vs LangChain

AutoGen is an open-source framework developed by Microsoft for building multi-agent AI systems and advanced LLM-powered applications.

It enables developers to create autonomous agents that can collaborate, converse, and solve problems together, or with human feedback integrated into the loop.

AutoGen provides abstractions for defining roles, tasks, and communication protocols between agents, allowing flexible setups from simple assistants to complex, multi-agent ecosystems.

It is designed for rapid prototyping as well as production deployment, with features like conversation orchestration, human-AI collaboration, and tool integration.

LangChain is one of the most widely adopted frameworks for building applications powered by large language models (LLMs). It simplifies the development of AI agents and workflows by providing modular components for connecting LLMs with external data sources, APIs, and memory.

LangChain enables developers to design chatbots, research assistants, and automation systems that move beyond static prompts into dynamic, context-aware applications.

Its architecture supports chains (sequences of prompts), agents (LLM-driven decision-makers), and tools (integrations such as APIs, databases, or search engines).

LangChain also offers integrations with vector databases, enabling retrieval-augmented generation (RAG) for more accurate, knowledge-grounded responses.